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Interleukin 23 receptor is essential for terminal differentiation of effector T helper type 17 cells in vivo

Interleukin 23 (IL-23) is required for autoimmune inflammation mediated by T helper type 17 cells (TH-17 cells) and is implicated in a number of human immune disorders. Here we restricted IL-23 receptor (IL-23R) deficiency to defined cell populations in vivo to investigate the requirement for IL-23...

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Hlavní autoři: McGeachy, Mandy J, Chen, Yi, Tato, Cristina M, Laurence, Arian, Joyce-Shaikh, Barbara, Blumenschein, Wendy, McClanahan, Terrill, O’Shea, John J, Cua, Daniel J
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2945605/
https://ncbi.nlm.nih.gov/pubmed/19182808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.1698
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