IL-23-Independent IL-17 Production Regulates Intestinal Epithelial Permeability

Whether IL-17A has pathogenic and/or protective roles in the gut mucosa is controversial and few studies have analyzed specific cell populations for protective functions within the inflamed colonic tissue. Here we provide evidence for IL-17A dependent regulation of the tight junction protein occludi...

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Detalhes bibliográficos
Publicado no:Immunity
Main Authors: Lee, Jacob S., Tato, Cristina M., Joyce-Shaikh, Barbara, Gulan, Fatih, Cayatte, Corinne, Chen, Yi, Blumenschein, Wendy M., Judo, Michael, Chen, Kevin, Ayanoglu, Gulesi, McClanahan, Terrill K., Li, Xiaoxia, Cua, Daniel J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6044435/
https://ncbi.nlm.nih.gov/pubmed/26431948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2015.09.003
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