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Distinct Regulation of IL-17 in Human Helper T Lymphocytes

OBJECTIVE: IL-17 producing helper T cells have been proposed to represent a separate lineage of CD4(+) cells, designated Th17 cells, which are regulated by the transcription factor RORγt. However, despite advances in understanding murine Th17 differentiation, a systematic assessment of factors that...

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Detalhes bibliográficos
Main Authors: Chen, Zhi, Tato, Cristina M., Muul, Linda, Laurence, Arian, O’Shea, John J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2323677/
https://ncbi.nlm.nih.gov/pubmed/17763419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.22866
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