Immune Response Mechanisms against AAV Vectors in Animal Models

由 Martino, Ashley T., Markusic, David M.
發表在 Mol Ther Methods Clin Dev (2019)

Liver-Directed Adeno-Associated Viral Gene Therapy for Hemophilia

由 Markusic, David M., Herzog, Roland W
出版 2012

Separating Lentiviral Vector Injection and Induction of Gene Expression in Time, Does Not Prevent an Immune Response to rtTA in Rats

由 Markusic, David M., de Waart, Dirk R., Seppen, Jurgen
出版 2010

Liver Induced Transgene Tolerance with AAV Vectors

由 Keeler, Geoffrey D., Markusic, David M., Hoffman, Brad E.
發表在 Cell Immunol (2017)

Update on clinical gene therapy for hemophilia

由 Perrin, George Q., Herzog, Roland W., Markusic, David M.
發表在 Blood (2019)

Development of gene transfer for induction of antigen-specific tolerance

由 Sack, Brandon K, Herzog, Roland W, Terhorst, Cox, Markusic, David M
發表在 Mol Ther Methods Clin Dev (2014)

Immunology of Gene and Cell Therapy

由 Markusic, David M., Martino, Ashley T., Porada, Christopher D., VandenDriessche, Thierry
發表在 Mol Ther (2020)

AAV Vector Biology in Primates: Finding the Missing Link?

由 Herzog, Roland W, Davidoff, Andrew M, Markusic, David M, Nathwani, Amit C
出版 2011

An Immune-Competent Murine Model to Study Elimination of AAV-Transduced Hepatocytes by Capsid-Specific CD8(+) T Cells

由 Palaschak, Brett, Marsic, Damien, Herzog, Roland W., Zolotukhin, Sergei, Markusic, David M.
發表在 Mol Ther Methods Clin Dev (2017)

B Cell Depletion Eliminates FVIII Memory B Cells and Enhances AAV8-coF8 Immune Tolerance Induction When Combined With Rapamycin

由 Biswas, Moanaro, Palaschak, Brett, Kumar, Sandeep R. P., Rana, Jyoti, Markusic, David M.
發表在 Front Immunol (2020)

Clinical development of gene therapy: results and lessons from recent successes

由 Kumar, Sandeep RP, Markusic, David M, Biswas, Moanaro, High, Katherine A, Herzog, Roland W
發表在 Mol Ther Methods Clin Dev (2016)

Tolerance Induction to Factor VIII by Transient Co-administration with Rapamycin

由 Moghimi, Babak, Sack, Brandon K., Nayak, Sushrusha, Markusic, David M., Mah, Cathryn S., Herzog, Roland W.
出版 2011

Reduction of liver macrophage transduction by pseudotyping lentiviral vectors with a fusion envelope from Autographa californica GP64 and Sendai virus F2 domain

由 Markusic, David M, van Til, Niek P, Hiralall, Johan K, Elferink, Ronald PJ Oude, Seppen, Jurgen
出版 2009

Potential for cellular stress response to hepatic factor VIII expression from AAV vector

由 Zolotukhin, Irene, Markusic, David M, Palaschak, Brett, Hoffman, Brad E, Srikanthan, Meera A, Herzog, Roland W
發表在 Mol Ther Methods Clin Dev (2016)

Combination Therapy for Inhibitor Reversal in Haemophilia A Using Monoclonal Anti-CD20 and Rapamycin

由 Biswas, Moanaro, Rogers, Geoffrey L., Sherman, Alexandra, Byrne, Barry J., Markusic, David M., Jiang, Haiyan, Herzog, Roland W.
發表在 Thromb Haemost (2016)

Gene Therapy-Induced Antigen-Specific Tregs Inhibit Neuro-inflammation and Reverse Disease in a Mouse Model of Multiple Sclerosis

由 Keeler, Geoffrey D., Kumar, Sandeep, Palaschak, Brett, Silverberg, Emily L., Markusic, David M., Jones, Noah T., Hoffman, Brad E.
發表在 Mol Ther (2018)

Transient B Cell Depletion or Improved Transgene Expression by Codon Optimization Promote Tolerance to Factor VIII in Gene Therapy

由 Sack, Brandon K., Merchant, Sherin, Markusic, David M., Nathwani, Amit C., Davidoff, Andrew M., Byrne, Barry J., Herzog, Roland W.
出版 2012

Adeno-Associated Virus D-Sequence-Mediated Suppression of Expression of a Human Major Histocompatibility Class II Gene: Implications in the Development of Adeno-Associated Virus Ve...

由 Kwon, Hyung-Joo, Qing, Keyun, Ponnazhagan, Selvarangan, Wang, Xu-Shan, Markusic, David M., Gupte, Siddhant, Boye, Shannon E., Srivastava, Arun
發表在 Hum Gene Ther (2020)

Vector Design Tour de Force: Integrating Combinatorial and Rational Approaches to Derive Novel Adeno-associated Virus Variants

由 Marsic, Damien, Govindasamy, Lakshmanan, Currlin, Seth, Markusic, David M, Tseng, Yu-Shan, Herzog, Roland W, Agbandje-McKenna, Mavis, Zolotukhin, Sergei
發表在 Mol Ther (2014)

Development of a Clinical Candidate AAV3 Vector for Gene Therapy of Hemophilia B

由 Brown, Harrison C., Doering, Christopher B., Herzog, Roland W., Ling, Chen, Markusic, David M., Spencer, H. Trent, Srivastava, Alok, Srivastava, Arun
發表在 Hum Gene Ther (2020)