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Liver Induced Transgene Tolerance with AAV Vectors

Immune tolerance is a vital component of immunity, as persistent activation of immune cells causes significant tissue damage and loss of tolerance leads to autoimmunity. Likewise, unwanted immune responses can occur in inherited disorders, such as hemophilia and Pompe disease, in which patients lack...

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Détails bibliographiques
Publié dans:Cell Immunol
Auteurs principaux: Keeler, Geoffrey D., Markusic, David M., Hoffman, Brad E.
Format: Artigo
Langue:Inglês
Publié: 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5988960/
https://ncbi.nlm.nih.gov/pubmed/29576315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellimm.2017.12.002
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