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Liver Induced Transgene Tolerance with AAV Vectors

Immune tolerance is a vital component of immunity, as persistent activation of immune cells causes significant tissue damage and loss of tolerance leads to autoimmunity. Likewise, unwanted immune responses can occur in inherited disorders, such as hemophilia and Pompe disease, in which patients lack...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Immunol
Prif Awduron: Keeler, Geoffrey D., Markusic, David M., Hoffman, Brad E.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5988960/
https://ncbi.nlm.nih.gov/pubmed/29576315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellimm.2017.12.002
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