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Liver Induced Transgene Tolerance with AAV Vectors
Immune tolerance is a vital component of immunity, as persistent activation of immune cells causes significant tissue damage and loss of tolerance leads to autoimmunity. Likewise, unwanted immune responses can occur in inherited disorders, such as hemophilia and Pompe disease, in which patients lack...
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| Veröffentlicht in: | Cell Immunol |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5988960/ https://ncbi.nlm.nih.gov/pubmed/29576315 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellimm.2017.12.002 |
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