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Liver Induced Transgene Tolerance with AAV Vectors

Immune tolerance is a vital component of immunity, as persistent activation of immune cells causes significant tissue damage and loss of tolerance leads to autoimmunity. Likewise, unwanted immune responses can occur in inherited disorders, such as hemophilia and Pompe disease, in which patients lack...

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Detalhes bibliográficos
Publicado no:Cell Immunol
Main Authors: Keeler, Geoffrey D., Markusic, David M., Hoffman, Brad E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5988960/
https://ncbi.nlm.nih.gov/pubmed/29576315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellimm.2017.12.002
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