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AAV3-miRNA vectors for growth suppression of human hepatocellular carcinoma cells in vitro and human liver tumors in a murine xenograft model in vivo

We have previously reported that recombinant adeno-associated virus serotype 3 (AAV3) vectors transduce human liver tumors more efficiently in a mouse xenograft model following systemic administration. Others have utilized AAV8 vectors expressing miR-26a and miR-122 to achieve near total inhibition...

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Dades bibliogràfiques
Publicat a:Gene Ther
Autors principals: Yin, Ling, Keeler, Geoffrey D., Zhang, Yuanhui, Hoffman, Brad E., Ling, Chen, Qing, Keyun, Srivastava, Arun
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7784898/
https://ncbi.nlm.nih.gov/pubmed/32152434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41434-020-0140-1
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