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Tolerance Induction to Factor VIII by Transient Co-administration with Rapamycin
BACKGROUND: Formation of inhibitory antibodies is a frequent and serious complication of factor VIII (F.VIII) replacement therapy for the X-linked bleeding disorder hemophilia A. Similarly, hemophilia A mice develop high-titer inhibitors to recombinant human F.VIII after a few intravenous injections...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3154987/ https://ncbi.nlm.nih.gov/pubmed/21585650 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1538-7836.2011.04351.x |
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