Synergy between rapamycin and FLT3 ligand enhances plasmacytoid dendritic cell–dependent induction of CD4(+)CD25(+)FoxP3(+) Treg

CD4(+)CD25(+)FoxP3(+) regulatory T cells (Treg) are critical elements for maintaining immune tolerance, for instance to exogenous antigens that are introduced during therapeutic interventions such as cell/organ transplant or gene/protein replacement therapy. Coadministration of antigen with rapamyci...

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Publicat a:Blood
Autors principals: Biswas, Moanaro, Sarkar, Debalina, Kumar, Sandeep R. P., Nayak, Sushrusha, Rogers, Geoffrey L., Markusic, David M., Liao, Gongxian, Terhorst, Cox, Herzog, Roland W.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2015
Matèries:
Immunobiology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4424416/
https://ncbi.nlm.nih.gov/pubmed/25833958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-09-599266
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