GITR engagement preferentially enhances proliferation of functionally competent CD4(+)CD25(+)FoxP3(+) regulatory T cells

Naturally occurring regulatory T cells (Treg) express high levels of glucocorticoid-induced tumour necrosis factor receptor (GITR). However, studies of the role of GITR in Treg biology has been complicated by the observation that upon activation effector CD4(+) T (Teff) cells also express the recept...

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Detalhes bibliográficos
Main Authors: Liao, Gongxian, Nayak, Sushrusha, Regueiro, Jose R., Berger, Scott B., Detre, Cynthia, Romero, Xavier, de Waal Malefyt, Rene, Chatila, Talal A., Herzog, Roland W., Terhorst, Cox
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Original Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2845330/
https://ncbi.nlm.nih.gov/pubmed/20139172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/intimm/dxq001
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