An Immune-Competent Murine Model to Study Elimination of AAV-Transduced Hepatocytes by Capsid-Specific CD8(+) T Cells

Por Palaschak, Brett, Marsic, Damien, Herzog, Roland W., Zolotukhin, Sergei, Markusic, David M.
Publicado no Mol Ther Methods Clin Dev (2017)

B Cell Depletion Eliminates FVIII Memory B Cells and Enhances AAV8-coF8 Immune Tolerance Induction When Combined With Rapamycin

Por Biswas, Moanaro, Palaschak, Brett, Kumar, Sandeep R. P., Rana, Jyoti, Markusic, David M.
Publicado no Front Immunol (2020)

Potential for cellular stress response to hepatic factor VIII expression from AAV vector

Por Zolotukhin, Irene, Markusic, David M, Palaschak, Brett, Hoffman, Brad E, Srikanthan, Meera A, Herzog, Roland W
Publicado no Mol Ther Methods Clin Dev (2016)

Gene Therapy-Induced Antigen-Specific Tregs Inhibit Neuro-inflammation and Reverse Disease in a Mouse Model of Multiple Sclerosis

Por Keeler, Geoffrey D., Kumar, Sandeep, Palaschak, Brett, Silverberg, Emily L., Markusic, David M., Jones, Noah T., Hoffman, Brad E.
Publicado no Mol Ther (2018)

Evaluation of engineered AAV capsids for hepatic factor IX gene transfer in murine and canine models

Por Markusic, David M., Nichols, Timothy C., Merricks, Elizabeth P., Palaschak, Brett, Zolotukhin, Irene, Marsic, Damien, Zolotukhin, Sergei, Srivastava, Arun, Herzog, Roland W.
Publicado no J Transl Med (2017)