Immune Response Mechanisms against AAV Vectors in Animal Models

Bằng Martino, Ashley T., Markusic, David M.
Xuất bản năm Mol Ther Methods Clin Dev (2019)

Liver-Directed Adeno-Associated Viral Gene Therapy for Hemophilia

Bằng Markusic, David M., Herzog, Roland W
Được phát hành 2012

Separating Lentiviral Vector Injection and Induction of Gene Expression in Time, Does Not Prevent an Immune Response to rtTA in Rats

Bằng Markusic, David M., de Waart, Dirk R., Seppen, Jurgen
Được phát hành 2010

Liver Induced Transgene Tolerance with AAV Vectors

Bằng Keeler, Geoffrey D., Markusic, David M., Hoffman, Brad E.
Xuất bản năm Cell Immunol (2017)

Update on clinical gene therapy for hemophilia

Bằng Perrin, George Q., Herzog, Roland W., Markusic, David M.
Xuất bản năm Blood (2019)

Development of gene transfer for induction of antigen-specific tolerance

Bằng Sack, Brandon K, Herzog, Roland W, Terhorst, Cox, Markusic, David M
Xuất bản năm Mol Ther Methods Clin Dev (2014)

Immunology of Gene and Cell Therapy

Bằng Markusic, David M., Martino, Ashley T., Porada, Christopher D., VandenDriessche, Thierry
Xuất bản năm Mol Ther (2020)

AAV Vector Biology in Primates: Finding the Missing Link?

Bằng Herzog, Roland W, Davidoff, Andrew M, Markusic, David M, Nathwani, Amit C
Được phát hành 2011

An Immune-Competent Murine Model to Study Elimination of AAV-Transduced Hepatocytes by Capsid-Specific CD8(+) T Cells

Bằng Palaschak, Brett, Marsic, Damien, Herzog, Roland W., Zolotukhin, Sergei, Markusic, David M.
Xuất bản năm Mol Ther Methods Clin Dev (2017)

B Cell Depletion Eliminates FVIII Memory B Cells and Enhances AAV8-coF8 Immune Tolerance Induction When Combined With Rapamycin

Bằng Biswas, Moanaro, Palaschak, Brett, Kumar, Sandeep R. P., Rana, Jyoti, Markusic, David M.
Xuất bản năm Front Immunol (2020)

Clinical development of gene therapy: results and lessons from recent successes

Bằng Kumar, Sandeep RP, Markusic, David M, Biswas, Moanaro, High, Katherine A, Herzog, Roland W
Xuất bản năm Mol Ther Methods Clin Dev (2016)

Tolerance Induction to Factor VIII by Transient Co-administration with Rapamycin

Bằng Moghimi, Babak, Sack, Brandon K., Nayak, Sushrusha, Markusic, David M., Mah, Cathryn S., Herzog, Roland W.
Được phát hành 2011

Reduction of liver macrophage transduction by pseudotyping lentiviral vectors with a fusion envelope from Autographa californica GP64 and Sendai virus F2 domain

Bằng Markusic, David M, van Til, Niek P, Hiralall, Johan K, Elferink, Ronald PJ Oude, Seppen, Jurgen
Được phát hành 2009

Potential for cellular stress response to hepatic factor VIII expression from AAV vector

Bằng Zolotukhin, Irene, Markusic, David M, Palaschak, Brett, Hoffman, Brad E, Srikanthan, Meera A, Herzog, Roland W
Xuất bản năm Mol Ther Methods Clin Dev (2016)

Combination Therapy for Inhibitor Reversal in Haemophilia A Using Monoclonal Anti-CD20 and Rapamycin

Bằng Biswas, Moanaro, Rogers, Geoffrey L., Sherman, Alexandra, Byrne, Barry J., Markusic, David M., Jiang, Haiyan, Herzog, Roland W.
Xuất bản năm Thromb Haemost (2016)

Gene Therapy-Induced Antigen-Specific Tregs Inhibit Neuro-inflammation and Reverse Disease in a Mouse Model of Multiple Sclerosis

Bằng Keeler, Geoffrey D., Kumar, Sandeep, Palaschak, Brett, Silverberg, Emily L., Markusic, David M., Jones, Noah T., Hoffman, Brad E.
Xuất bản năm Mol Ther (2018)

Transient B Cell Depletion or Improved Transgene Expression by Codon Optimization Promote Tolerance to Factor VIII in Gene Therapy

Bằng Sack, Brandon K., Merchant, Sherin, Markusic, David M., Nathwani, Amit C., Davidoff, Andrew M., Byrne, Barry J., Herzog, Roland W.
Được phát hành 2012

Adeno-Associated Virus D-Sequence-Mediated Suppression of Expression of a Human Major Histocompatibility Class II Gene: Implications in the Development of Adeno-Associated Virus Ve...

Bằng Kwon, Hyung-Joo, Qing, Keyun, Ponnazhagan, Selvarangan, Wang, Xu-Shan, Markusic, David M., Gupte, Siddhant, Boye, Shannon E., Srivastava, Arun
Xuất bản năm Hum Gene Ther (2020)

Vector Design Tour de Force: Integrating Combinatorial and Rational Approaches to Derive Novel Adeno-associated Virus Variants

Bằng Marsic, Damien, Govindasamy, Lakshmanan, Currlin, Seth, Markusic, David M, Tseng, Yu-Shan, Herzog, Roland W, Agbandje-McKenna, Mavis, Zolotukhin, Sergei
Xuất bản năm Mol Ther (2014)

Development of a Clinical Candidate AAV3 Vector for Gene Therapy of Hemophilia B

Bằng Brown, Harrison C., Doering, Christopher B., Herzog, Roland W., Ling, Chen, Markusic, David M., Spencer, H. Trent, Srivastava, Alok, Srivastava, Arun
Xuất bản năm Hum Gene Ther (2020)