Immune Response Mechanisms against AAV Vectors in Animal Models

по Martino, Ashley T., Markusic, David M.
Опубликовано в: Mol Ther Methods Clin Dev (2019)

Liver-Directed Adeno-Associated Viral Gene Therapy for Hemophilia

по Markusic, David M., Herzog, Roland W
Опубликовано 2012

Separating Lentiviral Vector Injection and Induction of Gene Expression in Time, Does Not Prevent an Immune Response to rtTA in Rats

по Markusic, David M., de Waart, Dirk R., Seppen, Jurgen
Опубликовано 2010

Liver Induced Transgene Tolerance with AAV Vectors

по Keeler, Geoffrey D., Markusic, David M., Hoffman, Brad E.
Опубликовано в: Cell Immunol (2017)

Update on clinical gene therapy for hemophilia

по Perrin, George Q., Herzog, Roland W., Markusic, David M.
Опубликовано в: Blood (2019)

Development of gene transfer for induction of antigen-specific tolerance

по Sack, Brandon K, Herzog, Roland W, Terhorst, Cox, Markusic, David M
Опубликовано в: Mol Ther Methods Clin Dev (2014)

Immunology of Gene and Cell Therapy

по Markusic, David M., Martino, Ashley T., Porada, Christopher D., VandenDriessche, Thierry
Опубликовано в: Mol Ther (2020)

AAV Vector Biology in Primates: Finding the Missing Link?

по Herzog, Roland W, Davidoff, Andrew M, Markusic, David M, Nathwani, Amit C
Опубликовано 2011

An Immune-Competent Murine Model to Study Elimination of AAV-Transduced Hepatocytes by Capsid-Specific CD8(+) T Cells

по Palaschak, Brett, Marsic, Damien, Herzog, Roland W., Zolotukhin, Sergei, Markusic, David M.
Опубликовано в: Mol Ther Methods Clin Dev (2017)

B Cell Depletion Eliminates FVIII Memory B Cells and Enhances AAV8-coF8 Immune Tolerance Induction When Combined With Rapamycin

по Biswas, Moanaro, Palaschak, Brett, Kumar, Sandeep R. P., Rana, Jyoti, Markusic, David M.
Опубликовано в: Front Immunol (2020)

Clinical development of gene therapy: results and lessons from recent successes

по Kumar, Sandeep RP, Markusic, David M, Biswas, Moanaro, High, Katherine A, Herzog, Roland W
Опубликовано в: Mol Ther Methods Clin Dev (2016)

Tolerance Induction to Factor VIII by Transient Co-administration with Rapamycin

по Moghimi, Babak, Sack, Brandon K., Nayak, Sushrusha, Markusic, David M., Mah, Cathryn S., Herzog, Roland W.
Опубликовано 2011

Reduction of liver macrophage transduction by pseudotyping lentiviral vectors with a fusion envelope from Autographa californica GP64 and Sendai virus F2 domain

по Markusic, David M, van Til, Niek P, Hiralall, Johan K, Elferink, Ronald PJ Oude, Seppen, Jurgen
Опубликовано 2009

Potential for cellular stress response to hepatic factor VIII expression from AAV vector

по Zolotukhin, Irene, Markusic, David M, Palaschak, Brett, Hoffman, Brad E, Srikanthan, Meera A, Herzog, Roland W
Опубликовано в: Mol Ther Methods Clin Dev (2016)

Combination Therapy for Inhibitor Reversal in Haemophilia A Using Monoclonal Anti-CD20 and Rapamycin

по Biswas, Moanaro, Rogers, Geoffrey L., Sherman, Alexandra, Byrne, Barry J., Markusic, David M., Jiang, Haiyan, Herzog, Roland W.
Опубликовано в: Thromb Haemost (2016)

Gene Therapy-Induced Antigen-Specific Tregs Inhibit Neuro-inflammation and Reverse Disease in a Mouse Model of Multiple Sclerosis

по Keeler, Geoffrey D., Kumar, Sandeep, Palaschak, Brett, Silverberg, Emily L., Markusic, David M., Jones, Noah T., Hoffman, Brad E.
Опубликовано в: Mol Ther (2018)

Transient B Cell Depletion or Improved Transgene Expression by Codon Optimization Promote Tolerance to Factor VIII in Gene Therapy

по Sack, Brandon K., Merchant, Sherin, Markusic, David M., Nathwani, Amit C., Davidoff, Andrew M., Byrne, Barry J., Herzog, Roland W.
Опубликовано 2012

Adeno-Associated Virus D-Sequence-Mediated Suppression of Expression of a Human Major Histocompatibility Class II Gene: Implications in the Development of Adeno-Associated Virus Ve...

по Kwon, Hyung-Joo, Qing, Keyun, Ponnazhagan, Selvarangan, Wang, Xu-Shan, Markusic, David M., Gupte, Siddhant, Boye, Shannon E., Srivastava, Arun
Опубликовано в: Hum Gene Ther (2020)

Vector Design Tour de Force: Integrating Combinatorial and Rational Approaches to Derive Novel Adeno-associated Virus Variants

по Marsic, Damien, Govindasamy, Lakshmanan, Currlin, Seth, Markusic, David M, Tseng, Yu-Shan, Herzog, Roland W, Agbandje-McKenna, Mavis, Zolotukhin, Sergei
Опубликовано в: Mol Ther (2014)

Development of a Clinical Candidate AAV3 Vector for Gene Therapy of Hemophilia B

по Brown, Harrison C., Doering, Christopher B., Herzog, Roland W., Ling, Chen, Markusic, David M., Spencer, H. Trent, Srivastava, Alok, Srivastava, Arun
Опубликовано в: Hum Gene Ther (2020)