Chaperones as Suppressors of Protein Misfolded Oligomer Toxicity

بواسطة Mannini, Benedetta, Chiti, Fabrizio
الحاوية / القاعدة Front Mol Neurosci (2017)

Single molecule secondary structure determination of proteins through infrared absorption nanospectroscopy

بواسطة Ruggeri, Francesco Simone, Mannini, Benedetta, Schmid, Roman, Vendruscolo, Michele, Knowles, Tuomas P. J.
الحاوية / القاعدة Nat Commun (2020)

Delivery of Native Proteins into C. elegans Using a Transduction Protocol Based on Lipid Vesicles

بواسطة Perni, Michele, Aprile, Francesco A., Casford, Sam, Mannini, Benedetta, Sormanni, Pietro, Dobson, Christopher M., Vendruscolo, Michele
الحاوية / القاعدة Sci Rep (2017)

Aβ Oligomers Dysregulate Calcium Homeostasis by Mechanosensitive Activation of AMPA and NMDA Receptors

بواسطة Fani, Giulia, Mannini, Benedetta, Vecchi, Giulia, Cascella, Roberta, Cecchi, Cristina, Dobson, Christopher M., Vendruscolo, Michele, Chiti, Fabrizio
الحاوية / القاعدة ACS Chem Neurosci (2021)

Exogenous misfolded protein oligomers can cross the intestinal barrier and cause a disease phenotype in C. elegans

بواسطة Perni, Michele, Mannini, Benedetta, Xu, Catherine K., Kumita, Janet R., Dobson, Christopher M., Chiti, Fabrizio, Vendruscolo, Michele
الحاوية / القاعدة Sci Rep (2021)

Proteome-wide observation of the phenomenon of life on the edge of solubility

بواسطة Vecchi, Giulia, Sormanni, Pietro, Mannini, Benedetta, Vandelli, Andrea, Tartaglia, Gian Gaetano, Dobson, Christopher M., Hartl, F. Ulrich, Vendruscolo, Michele
الحاوية / القاعدة Proc Natl Acad Sci U S A (2020)

Large Proteins Have a Great Tendency to Aggregate but a Low Propensity to Form Amyloid Fibrils

بواسطة Ramshini, Hassan, Parrini, Claudia, Relini, Annalisa, Zampagni, Mariagioia, Mannini, Benedetta, Pesce, Alessandra, Saboury, Ali Akbar, Nemat-Gorgani, Mohsen, Chiti, Fabrizio
منشور في 2011

Toxic HypF-N Oligomers Selectively Bind the Plasma Membrane to Impair Cell Adhesion Capability

بواسطة Oropesa-Nuñez, Reinier, Keshavan, Sandeep, Dante, Silvia, Diaspro, Alberto, Mannini, Benedetta, Capitini, Claudia, Cecchi, Cristina, Stefani, Massimo, Chiti, Fabrizio, Canale, Claudio
الحاوية / القاعدة Biophys J (2018)

Two human metabolites rescue a C. elegans model of Alzheimer’s disease via a cytosolic unfolded protein response

بواسطة Joshi, Priyanka, Perni, Michele, Limbocker, Ryan, Mannini, Benedetta, Casford, Sam, Chia, Sean, Habchi, Johnny, Labbadia, Johnathan, Dobson, Christopher M., Vendruscolo, Michele
الحاوية / القاعدة Commun Biol (2021)

Publisher Correction: Two human metabolites rescue a C. elegans model of Alzheimer’s disease via a cytosolic unfolded protein response

بواسطة Joshi, Priyanka, Perni, Michele, Limbocker, Ryan, Mannini, Benedetta, Casford, Sam, Chia, Sean, Habchi, Johnny, Labbadia, Johnathan, Dobson, Christopher M., Vendruscolo, Michele
الحاوية / القاعدة Commun Biol (2021)

Therapeutic Strategies to Reduce the Toxicity of Misfolded Protein Oligomers

بواسطة Kreiser, Ryan P., Wright, Aidan K., Block, Natalie R., Hollows, Jared E., Nguyen, Lam T., LeForte, Kathleen, Mannini, Benedetta, Vendruscolo, Michele, Limbocker, Ryan
الحاوية / القاعدة Int J Mol Sci (2020)

A comparison of the biochemical modifications caused by toxic and non-toxic protein oligomers in cells

بواسطة Zampagni, Mariagioia, Cascella, Roberta, Casamenti, Fiorella, Grossi, Cristina, Evangelisti, Elisa, Wright, Daniel, Becatti, Matteo, Liguri, Gianfranco, Mannini, Benedetta, Campioni, Silvia, Chiti, Fabrizio, Cecchi, Cristina
الحاوية / القاعدة J Cell Mol Med (2011)

A rationally designed bicyclic peptide remodels Aβ42 aggregation in vitro and reduces its toxicity in a worm model of Alzheimer’s disease

بواسطة Ikenoue, Tatsuya, Aprile, Francesco A., Sormanni, Pietro, Ruggeri, Francesco S., Perni, Michele, Heller, Gabriella T., Haas, Christian P., Middel, Christoph, Limbocker, Ryan, Mannini, Benedetta, Michaels, Thomas C. T., Knowles, Tuomas P. J., Dobson, Christopher M., Vendruscolo, Michele
الحاوية / القاعدة Sci Rep (2020)

Molecular mechanisms used by chaperones to reduce the toxicity of aberrant protein oligomers

بواسطة Mannini, Benedetta, Cascella, Roberta, Zampagni, Mariagioia, van Waarde-Verhagen, Maria, Meehan, Sarah, Roodveldt, Cintia, Campioni, Silvia, Boninsegna, Matilde, Penco, Amanda, Relini, Annalisa, Kampinga, Harm H., Dobson, Christopher M., Wilson, Mark R., Cecchi, Cristina, Chiti, Fabrizio
منشور في 2012

Systematic development of small molecules to inhibit specific microscopic steps of Aβ42 aggregation in Alzheimer’s disease

بواسطة Habchi, Johnny, Chia, Sean, Limbocker, Ryan, Mannini, Benedetta, Ahn, Minkoo, Perni, Michele, Hansson, Oskar, Arosio, Paolo, Kumita, Janet R., Challa, Pavan Kumar, Cohen, Samuel I. A., Linse, Sara, Dobson, Christopher M., Knowles, Tuomas P. J., Vendruscolo, Michele
الحاوية / القاعدة Proc Natl Acad Sci U S A (2017)

A dopamine metabolite stabilizes neurotoxic amyloid-β oligomers

بواسطة Cataldi, Rodrigo, Chia, Sean, Pisani, Katarina, Ruggeri, Francesco S., Xu, Catherine K., Šneideris, Tomas, Perni, Michele, Sarwat, Sunehera, Joshi, Priyanka, Kumita, Janet R., Linse, Sara, Habchi, Johnny, Knowles, Tuomas P. J., Mannini, Benedetta, Dobson, Christopher M., Vendruscolo, Michele
الحاوية / القاعدة Commun Biol (2021)

Publisher Correction: A dopamine metabolite stabilizes neurotoxic amyloid-β oligomers

بواسطة Cataldi, Rodrigo, Chia, Sean, Pisani, Katarina, Ruggeri, Francesco S., Xu, Catherine K., Šneideris, Tomas, Perni, Michele, Sarwat, Sunehera, Joshi, Priyanka, Kumita, Janet R., Linse, Sara, Habchi, Johnny, Knowles, Tuomas P. J., Mannini, Benedetta, Dobson, Christopher M., Vendruscolo, Michele
الحاوية / القاعدة Commun Biol (2021)

Rationally Designed Antibodies as Research Tools to Study the Structure–Toxicity Relationship of Amyloid-β Oligomers

بواسطة Limbocker, Ryan, Mannini, Benedetta, Cataldi, Rodrigo, Chhangur, Shianne, Wright, Aidan K., Kreiser, Ryan P., Albright, J. Alex, Chia, Sean, Habchi, Johnny, Sormanni, Pietro, Kumita, Janet R., Ruggeri, Francesco S., Dobson, Christopher M., Chiti, Fabrizio, Aprile, Francesco A., Vendruscolo, Michele
الحاوية / القاعدة Int J Mol Sci (2020)

Small-molecule sequestration of amyloid-β as a drug discovery strategy for Alzheimer’s disease

بواسطة Heller, Gabriella T., Aprile, Francesco A., Michaels, Thomas C. T., Limbocker, Ryan, Perni, Michele, Ruggeri, Francesco Simone, Mannini, Benedetta, Löhr, Thomas, Bonomi, Massimiliano, Camilloni, Carlo, De Simone, Alfonso, Felli, Isabella C., Pierattelli, Roberta, Knowles, Tuomas P. J., Dobson, Christopher M., Vendruscolo, Michele
الحاوية / القاعدة Sci Adv (2020)

Rational design of a conformation-specific antibody for the quantification of Aβ oligomers

بواسطة Aprile, Francesco A., Sormanni, Pietro, Podpolny, Marina, Chhangur, Shianne, Needham, Lisa-Maria, Ruggeri, Francesco S., Perni, Michele, Limbocker, Ryan, Heller, Gabriella T., Sneideris, Tomas, Scheidt, Tom, Mannini, Benedetta, Habchi, Johnny, Lee, Steven F., Salinas, Patricia C., Knowles, Tuomas P. J., Dobson, Christopher M., Vendruscolo, Michele
الحاوية / القاعدة Proc Natl Acad Sci U S A (2020)