Therapeutic Strategies to Reduce the Toxicity of Misfolded Protein Oligomers

The aberrant aggregation of proteins is implicated in the onset and pathogenesis of a wide range of neurodegenerative disorders, including Alzheimer’s and Parkinson’s diseases. Mounting evidence indicates that misfolded protein oligomers produced as intermediates in the aggregation process are poten...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Kreiser, Ryan P., Wright, Aidan K., Block, Natalie R., Hollows, Jared E., Nguyen, Lam T., LeForte, Kathleen, Mannini, Benedetta, Vendruscolo, Michele, Limbocker, Ryan
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7696907/
https://ncbi.nlm.nih.gov/pubmed/33212787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21228651
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