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Rationally Designed Antibodies as Research Tools to Study the Structure–Toxicity Relationship of Amyloid-β Oligomers

Alzheimer’s disease is associated with the aggregation of the amyloid-β peptide (Aβ), resulting in the deposition of amyloid plaques in brain tissue. Recent scrutiny of the mechanisms by which Aβ aggregates induce neuronal dysfunction has highlighted the importance of the Aβ oligomers of this protei...

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書目詳細資料
發表在:Int J Mol Sci
Main Authors: Limbocker, Ryan, Mannini, Benedetta, Cataldi, Rodrigo, Chhangur, Shianne, Wright, Aidan K., Kreiser, Ryan P., Albright, J. Alex, Chia, Sean, Habchi, Johnny, Sormanni, Pietro, Kumita, Janet R., Ruggeri, Francesco S., Dobson, Christopher M., Chiti, Fabrizio, Aprile, Francesco A., Vendruscolo, Michele
格式: Artigo
語言:Inglês
出版: MDPI 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7352524/
https://ncbi.nlm.nih.gov/pubmed/32630615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21124542
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