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Two human metabolites rescue a C. elegans model of Alzheimer’s disease via a cytosolic unfolded protein response

Age-related changes in cellular metabolism can affect brain homeostasis, creating conditions that are permissive to the onset and progression of neurodegenerative disorders such as Alzheimer’s and Parkinson’s diseases. Although the roles of metabolites have been extensively studied with regard to ce...

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Bibliografische gegevens
Gepubliceerd in:Commun Biol
Hoofdauteurs: Joshi, Priyanka, Perni, Michele, Limbocker, Ryan, Mannini, Benedetta, Casford, Sam, Chia, Sean, Habchi, Johnny, Labbadia, Johnathan, Dobson, Christopher M., Vendruscolo, Michele
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2021
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8263720/
https://ncbi.nlm.nih.gov/pubmed/34234268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-021-02218-7
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