A dopamine metabolite stabilizes neurotoxic amyloid-β oligomers

Aberrant soluble oligomers formed by the amyloid-β peptide (Aβ) are major pathogenic agents in the onset and progression of Alzheimer’s disease. A variety of biomolecules can influence the formation of these oligomers in the brain, although their mechanisms of action are still largely unknown. Here,...

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發表在:Commun Biol
Main Authors: Cataldi, Rodrigo, Chia, Sean, Pisani, Katarina, Ruggeri, Francesco S., Xu, Catherine K., Šneideris, Tomas, Perni, Michele, Sarwat, Sunehera, Joshi, Priyanka, Kumita, Janet R., Linse, Sara, Habchi, Johnny, Knowles, Tuomas P. J., Mannini, Benedetta, Dobson, Christopher M., Vendruscolo, Michele
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2021
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7782527/
https://ncbi.nlm.nih.gov/pubmed/33398040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-020-01490-3
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