The Barium Site in a Potassium Channel by X-Ray Crystallography

por Jiang, Youxing, MacKinnon, Roderick
Publicado 2000

Voltage-dependent K(+) channel gating and voltage sensor toxin sensitivity depend on the mechanical state of the lipid membrane

por Schmidt, Daniel, MacKinnon, Roderick
Publicado 2008

Inferred motions of the S3a helix during voltage-dependent K(+) channel gating

por Banerjee, Anirban, MacKinnon, Roderick
Publicado 2008

Functional analysis of Kv1.2 and paddle chimera Kv channels in planar lipid bilayers

por Tao, Xiao, MacKinnon, Roderick
Publicado 2008

Cryo-EM structure of the open human ether-à-go-go related K(+) channel hERG

por Wang, Weiwei, MacKinnon, Roderick
Publicado en Cell (2017)

Cryo-EM structure of a KCNQ1/CaM complex reveals insights into congenital long QT syndrome

por Sun, Ji, MacKinnon, Roderick
Publicado en Cell (2017)

Structure of the CLC-1 chloride channel from Homo sapiens

por Park, Eunyong, MacKinnon, Roderick
Publicado en eLife (2018)

Cryo-EM structure of the KvAP channel reveals a non-domain-swapped voltage sensor topology

por Tao, Xiao, MacKinnon, Roderick
Publicado en eLife (2019)

Molecular structures of the human Slo1 K(+) channel in complex with β4

por Tao, Xiao, MacKinnon, Roderick
Publicado en eLife (2019)

Structural basis of human KCNQ1 modulation and gating

por Sun, Ji, MacKinnon, Roderick
Publicado en Cell (2019)

Isolation of a Single Carboxyl-Carboxylate Proton Binding Site in the Pore of a Cyclic Nucleotide–Gated Channel

por Morrill, James A., MacKinnon, Roderick
Publicado 1999

Solution structure and phospholipid interactions of the isolated voltage-sensor domain from KvAP

por Butterwick, Joel A., MacKinnon, Roderick
Publicado 2010

Crystal Structure of the Mammalian GIRK2 K(+) Channel and Gating Regulation by G-Proteins, PIP(2) and Sodium

por Whorton, Matthew R., MacKinnon, Roderick
Publicado 2011

X-ray structure of the mammalian GIRK2 – βγ G protein complex

por Whorton, Matthew R., MacKinnon, Roderick
Publicado en Nature (2013)

Structural titration of Slo2.2, a Na(+)-dependent K(+) channel

por Hite, Richard K, MacKinnon, Roderick
Publicado en Cell (2017)

Structure of the voltage-gated K(+) channel Eag1 reveals an alternative voltage sensing mechanism

por Whicher, Jonathan R., MacKinnon, Roderick
Publicado en Science (2016)

Structures of the human HCN1 hyperpolarization-activated channel

por Lee, Chia-Hsueh, MacKinnon, Roderick
Publicado en Cell (2017)

Structure-based membrane dome mechanism for Piezo mechanosensitivity

por Guo, Yusong R, MacKinnon, Roderick
Publicado en eLife (2017)

Activation mechanism of a human SK-calmodulin channel complex elucidated by cryo-EM structures

por Lee, Chia-Hsueh, MacKinnon, Roderick
Publicado en Science (2018)

Piezo’s membrane footprint and its contribution to mechanosensitivity

por Haselwandter, Christoph A, MacKinnon, Roderick
Publicado en eLife (2018)