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Crystal Structure of the Mammalian GIRK2 K(+) Channel and Gating Regulation by G-Proteins, PIP(2) and Sodium
G-protein-gated K(+) channels (Kir3.1–Kir3.4) control electrical excitability in many different cells. Among their functions relevant to human physiology and disease, they regulate the heart rate and govern a wide range of neuronal activities. Here we present the first crystal structures of a G-prot...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3243363/ https://ncbi.nlm.nih.gov/pubmed/21962516 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2011.07.046 |
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