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Cooperative regulation by G proteins and Na(+) of neuronal GIRK2 K(+) channels
G protein gated inward rectifier K(+) (GIRK) channels open and thereby silence cellular electrical activity when inhibitory G protein coupled receptors (GPCRs) are stimulated. Here we describe an assay to measure neuronal GIRK2 activity as a function of membrane-anchored G protein concentration. Usi...
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| Veröffentlicht in: | eLife |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
eLife Sciences Publications, Ltd
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4866826/ https://ncbi.nlm.nih.gov/pubmed/27074662 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.15751 |
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