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Structures of the human HCN1 hyperpolarization-activated channel
Hyperpolarization-activated cyclic nucleotide-gated (HCN) channels underlie the control of rhythmic activity in cardiac and neuronal pacemaker cells. In HCN, the polarity of voltage dependence is uniquely reversed. Intracellular cAMP levels tune the voltage response, enabling sympathetic nerve stimu...
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| Publicado en: | Cell |
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| Autores principales: | , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2017
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5496774/ https://ncbi.nlm.nih.gov/pubmed/28086084 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.12.023 |
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