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Structures of the human HCN1 hyperpolarization-activated channel
Hyperpolarization-activated cyclic nucleotide-gated (HCN) channels underlie the control of rhythmic activity in cardiac and neuronal pacemaker cells. In HCN, the polarity of voltage dependence is uniquely reversed. Intracellular cAMP levels tune the voltage response, enabling sympathetic nerve stimu...
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| 出版年: | Cell |
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| 主要な著者: | , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5496774/ https://ncbi.nlm.nih.gov/pubmed/28086084 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.12.023 |
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