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Voltage sensor movements during hyperpolarization in the HCN channel

The hyperpolarization-activated cyclic nucleotide-gated (HCN) channel is a voltage-gated cation channel that mediates neuronal and cardiac pacemaker activity. HCN exhibits reversed voltage dependence, meaning it closes with depolarization and opens with hyperpolarization. Different than Na(+), Ca(2+...

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Detalhes bibliográficos
Publicado no:Cell
Main Authors: Lee, Chia-Hsueh, MacKinnon, Roderick
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6911011/
https://ncbi.nlm.nih.gov/pubmed/31787376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2019.11.006
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