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The HCN Channel Voltage Sensor Undergoes A Large Downward Motion During Hyperpolarization
Voltage-gated ion channels (VGICs) contain positively-charged residues within the S4 helix of the voltage-sensing domain (VSD) that are displaced in response to changes in transmembrane voltage, promoting conformational changes that open the pore. Pacemaker HCN channels are unique among VGICs becaus...
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| Publicado no: | Nat Struct Mol Biol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6692172/ https://ncbi.nlm.nih.gov/pubmed/31285608 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41594-019-0259-1 |
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