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Molecular mechanism of voltage-dependent potentiation of KCNH potassium channels

EAG-like (ELK) voltage-gated potassium channels are abundantly expressed in the brain. These channels exhibit a behavior called voltage-dependent potentiation (VDP), which appears to be a specialization to dampen the hyperexitability of neurons. VDP manifests as a potentiation of current amplitude,...

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Bibliographische Detailangaben
Veröffentlicht in:eLife
Hauptverfasser: Dai, Gucan, Zagotta, William N
Format: Artigo
Sprache:Inglês
Veröffentlicht: eLife Sciences Publications, Ltd 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5440166/
https://ncbi.nlm.nih.gov/pubmed/28443815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.26355
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