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Voltage-dependent gating of KCNH potassium channels lacking a covalent link between voltage-sensing and pore domains

Voltage-gated channels open paths for ion permeation upon changes in membrane potential, but how voltage changes are coupled to gating is not entirely understood. Two modules can be recognized in voltage-gated potassium channels, one responsible for voltage sensing (transmembrane segments S1 to S4),...

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Publicat a:Nat Commun
Autors principals: Lörinczi, Éva, Gómez-Posada, Juan Camilo, de la Peña, Pilar, Tomczak, Adam P., Fernández-Trillo, Jorge, Leipscher, Ulrike, Stühmer, Walter, Barros, Francisco, Pardo, Luis A.
Format: Artigo
Idioma:Inglês
Publicat: Nature Pub. Group 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4389246/
https://ncbi.nlm.nih.gov/pubmed/25818916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7672
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