Voltage-dependent gating of KCNH potassium channels lacking a covalent link between voltage-sensing and pore domains

Voltage-gated channels open paths for ion permeation upon changes in membrane potential, but how voltage changes are coupled to gating is not entirely understood. Two modules can be recognized in voltage-gated potassium channels, one responsible for voltage sensing (transmembrane segments S1 to S4),...

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發表在:Nat Commun
Main Authors: Lörinczi, Éva, Gómez-Posada, Juan Camilo, de la Peña, Pilar, Tomczak, Adam P., Fernández-Trillo, Jorge, Leipscher, Ulrike, Stühmer, Walter, Barros, Francisco, Pardo, Luis A.
格式: Artigo
語言:Inglês
出版: Nature Pub. Group 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4389246/
https://ncbi.nlm.nih.gov/pubmed/25818916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7672
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