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Cryo-EM structure of the KvAP channel reveals a non-domain-swapped voltage sensor topology

Conductance in voltage-gated ion channels is regulated by membrane voltage through structural domains known as voltage sensors. A single structural class of voltage sensor domain exists, but two different modes of voltage sensor attachment to the pore occur in nature: domain-swapped and non-domain-s...

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Vydáno v:eLife
Hlavní autoři: Tao, Xiao, MacKinnon, Roderick
Médium: Artigo
Jazyk:Inglês
Vydáno: eLife Sciences Publications, Ltd 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6882556/
https://ncbi.nlm.nih.gov/pubmed/31755864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.52164
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