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Structure of the CLC-1 chloride channel from Homo sapiens

CLC channels mediate passive Cl(−) conduction, while CLC transporters mediate active Cl(−) transport coupled to H(+) transport in the opposite direction. The distinction between CLC-0/1/2 channels and CLC transporters seems undetectable by amino acid sequence. To understand why they are different fu...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Park, Eunyong, MacKinnon, Roderick
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6019066/
https://ncbi.nlm.nih.gov/pubmed/29809153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.36629
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