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Structure of a CLC chloride ion channel by cryo-electron microscopy

CLC proteins transport chloride (Cl(−)) ions across cellular membranes to regulate muscle excitability, electrolyte movement across epithelia, and acidification of intracellular organelles. Some CLC proteins are channels that conduct Cl(−) ions passively, whereas others are secondary active transpor...

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Pubblicato in:Nature
Autori principali: Park, Eunyong, Campbell, Ernest B., MacKinnon, Roderick
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5576512/
https://ncbi.nlm.nih.gov/pubmed/28002411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature20812
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