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Electron cryo-microscopy structure of the canonical TRPC4 ion channel

Canonical transient receptor channels (TRPC) are non-selective cation channels. They are involved in receptor-operated Ca(2+) signaling and have been proposed to act as store-operated channels (SOC). Their malfunction is related to cardiomyopathies and their modulation by small molecules has been sh...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Vinayagam, Deivanayagabarathy, Mager, Thomas, Apelbaum, Amir, Bothe, Arne, Merino, Felipe, Hofnagel, Oliver, Gatsogiannis, Christos, Raunser, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5951680/
https://ncbi.nlm.nih.gov/pubmed/29717981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.36615
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