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Structure of the human BBSome core complex

The BBSome is a heterooctameric protein complex that plays a central role in primary cilia homeostasis. Its malfunction causes the severe ciliopathy Bardet-Biedl syndrome (BBS). The complex acts as a cargo adapter that recognizes signaling proteins such as GPCRs and links them to the intraflagellar...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Klink, Björn Udo, Gatsogiannis, Christos, Hofnagel, Oliver, Wittinghofer, Alfred, Raunser, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7018512/
https://ncbi.nlm.nih.gov/pubmed/31951201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.53910
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