Structural basis of TRPC4 regulation by calmodulin and pharmacological agents

Canonical transient receptor potential channels (TRPC) are involved in receptor-operated and/or store-operated Ca(2+) signaling. Inhibition of TRPCs by small molecules was shown to be promising in treating renal diseases. In cells, the channels are regulated by calmodulin (CaM). Molecular details of...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:eLife
Main Authors: Vinayagam, Deivanayagabarathy, Quentin, Dennis, Yu-Strzelczyk, Jing, Sitsel, Oleg, Merino, Felipe, Stabrin, Markus, Hofnagel, Oliver, Yu, Maolin, Ledeboer, Mark W, Nagel, Georg, Malojcic, Goran, Raunser, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2020
Assuntos:
Structural Biology and Molecular Biophysics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7735759/
https://ncbi.nlm.nih.gov/pubmed/33236980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.60603
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados