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Structural basis of TRPC4 regulation by calmodulin and pharmacological agents
Canonical transient receptor potential channels (TRPC) are involved in receptor-operated and/or store-operated Ca(2+) signaling. Inhibition of TRPCs by small molecules was shown to be promising in treating renal diseases. In cells, the channels are regulated by calmodulin (CaM). Molecular details of...
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| 出版年: | eLife |
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| 主要な著者: | , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
eLife Sciences Publications, Ltd
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7735759/ https://ncbi.nlm.nih.gov/pubmed/33236980 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.60603 |
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