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Structural basis for pharmacological modulation of the TRPC6 channel
Transient receptor potential canonical (TRPC) proteins form nonselective cation channels that play physiological roles in a wide variety of cells. Despite growing evidence supporting the therapeutic potential of TRPC6 inhibition in treating pathological cardiac and renal conditions, mechanistic unde...
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| Publicado no: | eLife |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
eLife Sciences Publications, Ltd
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7082128/ https://ncbi.nlm.nih.gov/pubmed/32149605 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.53311 |
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