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Structure of the human lipid-gated cation channel TRPC3

The TRPC channels are crucially involved in store-operated calcium entry and calcium homeostasis, and they are implicated in human diseases such as neurodegenerative disease, cardiac hypertrophy, and spinocerebellar ataxia. We present a structure of the full-length human TRPC3, a lipid-gated TRPC me...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Fan, Chen, Choi, Wooyoung, Sun, Weinan, Du, Juan, Lü, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5967863/
https://ncbi.nlm.nih.gov/pubmed/29726814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.36852
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