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Molecular basis of force-from-lipids gating in the mechanosensitive channel MscS

Prokaryotic mechanosensitive (MS) channels open by sensing the physical state of the membrane. As such, lipid-protein interactions represent the defining molecular process underlying mechanotransduction. Here, we describe cryo-electron microscopy (cryo-EM) structures of the E. coli small-conductance...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Reddy, Bharat, Bavi, Navid, Lu, Allen, Park, Yeonwoo, Perozo, Eduardo
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7299334/
https://ncbi.nlm.nih.gov/pubmed/31880537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.50486
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