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Piezo’s membrane footprint and its contribution to mechanosensitivity

Piezo1 is an ion channel that gates open when mechanical force is applied to a cell membrane, thus allowing cells to detect and respond to mechanical stimulation. Molecular structures of Piezo1 reveal a large ion channel with an unusually curved shape. This study analyzes how such a curved ion chann...

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Dades bibliogràfiques
Publicat a:eLife
Autors principals: Haselwandter, Christoph A, MacKinnon, Roderick
Format: Artigo
Idioma:Inglês
Publicat: eLife Sciences Publications, Ltd 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6317911/
https://ncbi.nlm.nih.gov/pubmed/30480546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.41968
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