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Piezo’s membrane footprint and its contribution to mechanosensitivity

Piezo1 is an ion channel that gates open when mechanical force is applied to a cell membrane, thus allowing cells to detect and respond to mechanical stimulation. Molecular structures of Piezo1 reveal a large ion channel with an unusually curved shape. This study analyzes how such a curved ion chann...

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Detalles Bibliográficos
Publicado en:eLife
Main Authors: Haselwandter, Christoph A, MacKinnon, Roderick
Formato: Artigo
Idioma:Inglês
Publicado: eLife Sciences Publications, Ltd 2018
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6317911/
https://ncbi.nlm.nih.gov/pubmed/30480546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.41968
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