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Mechanosensitivity is mediated directly by the lipid membrane in TRAAK and TREK1 K(+) channels

Mechanosensitive ion channels underlie neuronal responses to physical forces in the sensation of touch, hearing, and other mechanical stimuli. The fundamental basis of force transduction in eukaryotic mechanosensitive ion channels is unknown. Are mechanical forces transmitted directly from membrane...

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Detalhes bibliográficos
Main Authors: Brohawn, Stephen G., Su, Zhenwei, MacKinnon, Roderick
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3948252/
https://ncbi.nlm.nih.gov/pubmed/24550493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1320768111
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