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Mechanosensitivity is mediated directly by the lipid membrane in TRAAK and TREK1 K(+) channels

Mechanosensitive ion channels underlie neuronal responses to physical forces in the sensation of touch, hearing, and other mechanical stimuli. The fundamental basis of force transduction in eukaryotic mechanosensitive ion channels is unknown. Are mechanical forces transmitted directly from membrane...

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書目詳細資料
Main Authors: Brohawn, Stephen G., Su, Zhenwei, MacKinnon, Roderick
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3948252/
https://ncbi.nlm.nih.gov/pubmed/24550493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1320768111
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