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Mechanosensitivity is mediated directly by the lipid membrane in TRAAK and TREK1 K(+) channels

Mechanosensitive ion channels underlie neuronal responses to physical forces in the sensation of touch, hearing, and other mechanical stimuli. The fundamental basis of force transduction in eukaryotic mechanosensitive ion channels is unknown. Are mechanical forces transmitted directly from membrane...

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Autors principals: Brohawn, Stephen G., Su, Zhenwei, MacKinnon, Roderick
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3948252/
https://ncbi.nlm.nih.gov/pubmed/24550493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1320768111
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