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Structural titration of Slo2.2, a Na(+)-dependent K(+) channel

The stable structural conformations that occur along the complete reaction coordinate for ion channel opening have never been observed. In this study we describe the equilibrium ensemble of structures of Slo2.2, a neuronal Na(+)-activated K(+) channel, as a function of the Na(+) concentration. We fi...

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Bibliografski detalji
Izdano u:Cell
Glavni autori: Hite, Richard K, MacKinnon, Roderick
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5382815/
https://ncbi.nlm.nih.gov/pubmed/28111072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.12.030
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