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Structural basis for gating the high conductance Ca(2+)-activated K(+) channel

The precise control of an ion channel’s gate by environmental stimuli is crucial to the fulfillment of its biological role. The gate in Slo1 channels is regulated by two separate stimuli, intracellular Ca(2+) concentration and membrane voltage. Thus, Slo1 is central to understanding the relationship...

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Bibliografiske detaljer
Udgivet i:Nature
Main Authors: Hite, Richard K., Tao, Xiao, MacKinnon, Roderick
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5513477/
https://ncbi.nlm.nih.gov/pubmed/27974801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature20775
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