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Structural basis for gating the high conductance Ca(2+)-activated K(+) channel

The precise control of an ion channel’s gate by environmental stimuli is crucial to the fulfillment of its biological role. The gate in Slo1 channels is regulated by two separate stimuli, intracellular Ca(2+) concentration and membrane voltage. Thus, Slo1 is central to understanding the relationship...

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Podrobná bibliografie
Vydáno v:Nature
Hlavní autoři: Hite, Richard K., Tao, Xiao, MacKinnon, Roderick
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5513477/
https://ncbi.nlm.nih.gov/pubmed/27974801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature20775
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