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Cryo-EM structure of the open high conductance Ca(2+)-activated K(+) channel
The Ca(2+)-activated K(+) channel, Slo1, has an unusually large conductance and contains a voltage sensor and multiple chemical sensors. Dual activation by voltage and Ca(2+) renders Slo1 central to numerous cellular processes that couple electrical signaling to Ca(2+)-mediated events such as muscle...
Enregistré dans:
Publié dans: | Nature |
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Auteurs principaux: | , , |
Format: | Artigo |
Langue: | Inglês |
Publié: |
2016
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5500982/ https://ncbi.nlm.nih.gov/pubmed/27974795 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature20608 |
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