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Cryo-EM structure of the open high conductance Ca(2+)-activated K(+) channel

The Ca(2+)-activated K(+) channel, Slo1, has an unusually large conductance and contains a voltage sensor and multiple chemical sensors. Dual activation by voltage and Ca(2+) renders Slo1 central to numerous cellular processes that couple electrical signaling to Ca(2+)-mediated events such as muscle...

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Enregistré dans:
Détails bibliographiques
Publié dans:Nature
Auteurs principaux: Tao, Xiao, Hite, Richard K., MacKinnon, Roderick
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5500982/
https://ncbi.nlm.nih.gov/pubmed/27974795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature20608
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