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Cryo-EM structure of the open high conductance Ca(2+)-activated K(+) channel
The Ca(2+)-activated K(+) channel, Slo1, has an unusually large conductance and contains a voltage sensor and multiple chemical sensors. Dual activation by voltage and Ca(2+) renders Slo1 central to numerous cellular processes that couple electrical signaling to Ca(2+)-mediated events such as muscle...
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| 發表在: | Nature |
|---|---|
| Main Authors: | , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2016
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5500982/ https://ncbi.nlm.nih.gov/pubmed/27974795 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature20608 |
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