Sialic Acid Metabolism: A Key Player in Breast Cancer Metastasis Revealed by Metabolomics

af Teoh, Shao Thing, Ogrodzinski, Martin P., Ross, Christina, Hunter, Kent W., Lunt, Sophia Y.
Udgivet i Front Oncol (2018)

Prediction of years of life after diagnosis of breast cancer using omics and omic-by-treatment interactions

af González-Reymúndez, Agustín, de los Campos, Gustavo, Gutiérrez, Lucía, Lunt, Sophia Y, Vazquez, Ana I
Udgivet i Eur J Hum Genet (2017)

Cysteine catabolism and the serine biosynthesis pathway support pyruvate production during pyruvate kinase knockdown in pancreatic cancer cells

af Yu, Lei, Teoh, Shao Thing, Ensink, Elliot, Ogrodzinski, Martin P., Yang, Che, Vazquez, Ana I., Lunt, Sophia Y.
Udgivet i Cancer Metab (2019)

Metformin induces distinct bioenergetic and metabolic profiles in sensitive versus resistant high grade serous ovarian cancer and normal fallopian tube secretory epithelial cells

af Hodeib, Melissa, Ogrodzinski, Martin P., Vergnes, Laurent, Reue, Karen, Karlan, Beth Y., Lunt, Sophia Y., Aspuria, Paul-Joseph P.
Udgivet i Oncotarget (2017)

Mitochondrial haplotype of the host stromal microenvironment alters metastasis in a non-cell autonomous manner

af Brinker, Amanda E., Vivian, Carolyn J., Beadnell, Thomas C., Koestler, Devin C., Teoh, Shao T., Lunt, Sophia Y., Welch, Danny R.
Udgivet i Cancer Res (2019)

Pyruvate Kinase Isoform Switching and Hepatic Metabolic Reprogramming by the Environmental Contaminant 2,3,7,8-Tetrachlorodibenzo-p-Dioxin

af Nault, Rance, Fader, Kelly A., Kirby, Mathew P., Ahmed, Shaimaa, Matthews, Jason, Jones, A. Daniel, Lunt, Sophia Y., Zacharewski, Timothy R.
Udgivet i Toxicol Sci (2016)

Anions for Near-Infrared Selective Organic Salt Photovoltaics

af Traverse, Christopher J., Young, Margaret, Suddard-Bangsund, John, Patrick, Tyler, Bates, Matthew, Chen, Pei, Wingate, Brian, Lunt, Sophia Y., Anctil, Annick, Lunt, Richard R.
Udgivet i Sci Rep (2017)

Dose-Dependent Metabolic Reprogramming and Differential Gene Expression in TCDD-Elicited Hepatic Fibrosis

af Nault, Rance, Fader, Kelly A., Ammendolia, Dustin A., Dornbos, Peter, Potter, Dave, Sharratt, Bonnie, Kumagai, Kazuyoshi, Harkema, Jack R., Lunt, Sophia Y., Matthews, Jason, Zacharewski, Tim
Udgivet i Toxicol Sci (2016)

Modulating cellular cytotoxicity and phototoxicity of fluorescent organic salts through counterion pairing

af Broadwater, Deanna, Bates, Matthew, Jayaram, Mayank, Young, Margaret, He, Jianzhou, Raithel, Austin L., Hamann, Thomas W., Zhang, Wei, Borhan, Babak, Lunt, Richard R., Lunt, Sophia Y.
Udgivet i Sci Rep (2019)

Succinate dehydrogenase inhibition leads to epithelial-mesenchymal transition and reprogrammed carbon metabolism

af Aspuria, Paul-Joseph P, Lunt, Sophia Y, Väremo, Leif, Vergnes, Laurent, Gozo, Maricel, Beach, Jessica A, Salumbides, Brenda, Reue, Karen, Wiedemeyer, W Ruprecht, Nielsen, Jens, Karlan, Beth Y, Orsulic, Sandra
Udgivet i Cancer Metab (2014)

Integrated analyses of murine breast cancer models reveal critical parallels with human disease

af Rennhack, Jonathan P., To, Briana, Swiatnicki, Matthew, Dulak, Caleb, Ogrodzinski, Martin P., Zhang, Yueqi, Li, Caralynn, Bylett, Evan, Ross, Christina, Szczepanek, Karol, Hanrahan, William, Jayatissa, Muthu, Lunt, Sophia Y., Hunter, Kent, Andrechek, Eran R.
Udgivet i Nat Commun (2019)

Balancing precision versus cohort transcriptomic analysis of acute and recovery phase of viral bronchiolitis

af Gupta, Ruchir, Leimanis, Mara L., Adams, Marie, Bachmann, André S., Uhl, Katie L., Bupp, Caleb P., Hartog, Nicholas L., Kort, Eric J., Olivero, Rosemary, Comstock, Sarah S., Sanfilippo, Dominic J., Lunt, Sophia Y., Prokop, Jeremy W., Rajasekaran, Surender
Udgivet i Am J Physiol Lung Cell Mol Physiol (2021)

Fatty acid carbon is essential for dNTP synthesis in endothelial cells

af Schoors, Sandra, Bruning, Ulrike, Missiaen, Rindert, Queiroz, Karla CS, Borgers, Gitte, Elia, Ilaria, Zecchin, Annalisa, Cantelmo, Anna Rita, Christen, Stefan, Goveia, Jermaine, Heggermont, Ward, Goddé, Lucica, Vinckier, Stefan, Van Veldhoven, Paul P., Eelen, Guy, Schoonjans, Luc, Gerhardt, Holger, Dewerchin, Mieke, Baes, Myriam, De Bock, Katrien, Ghesquière, Bart, Lunt, Sophia Y., Fendt, Sarah-Maria, Carmeliet, Peter
Udgivet i Nature (2015)

Development of a Colon Cancer GEMM-Derived Orthotopic Transplant Model for Drug Discovery and Validation

af Martin, Eric S., Belmont, Peter J., Sinnamon, Mark J., Richard, Larissa Georgeon, Yuan, Jing, Coffee, Erin M., Roper, Jatin, Lee, Lydia, Heidari, Pedram, Lunt, Sophia Y., Goel, Gautam, Ji, Christy, Xie, Julie, Xie, Tao, Lamb, John, Weinrich, Scott, VanArsdale, Todd, Bronson, Roderick T., Xavier, Ramnik J., Vander Heiden, Matthew G., Kan, Julie L. C., Mahmood, Umar, Hung, Kenneth E.
Udgivet 2013

Pyruvate kinase isoform expression alters nucleotide synthesis to impact cell proliferation

af Lunt, Sophia Y., Muralidhar, Vinayak, Hosios, Aaron M., Israelsen, William J., Gui, Dan Y., Newhouse, Lauren, Ogrodzinski, Martin, Hecht, Vivian, Xu, Kali, Acevedo, Paula N. Marín, Hollern, Daniel P., Bellinger, Gary, Dayton, Talya L., Christen, Stefan, Elia, Ilaria, Dinh, Anh T., Stephanopoulos, Gregory, Manalis, Scott R., Yaffe, Michael B., Andrechek, Eran R., Fendt, Sarah-Maria, Heiden, Matthew G. Vander
Udgivet i Mol Cell (2014)

A roadmap for interpreting (13)C metabolite labeling patterns from cells

af Buescher, Joerg M., Antoniewicz, Maciek R., Boros, Laszlo G., Burgess, Shawn C., Brunengraber, Henri, Clish, Clary B., DeBerardinis, Ralph J., Feron, Olivier, Frezza, Christian, Ghesquiere, Bart, Gottlieb, Eyal, Hiller, Karsten, Jones, Russell G., Kamphorst, Jurre J., Kibbey, Richard G., Kimmelman, Alec C., Locasale, Jason W., Lunt, Sophia Y., Maddocks, Oliver D. K., Malloy, Craig, Metallo, Christian M., Meuillet, Emmanuelle J., Munger, Joshua, Nöh, Katharina, Rabinowitz, Joshua D., Ralser, Markus, Sauer, Uwe, Stephanopoulos, Gregory, St-Pierre, Julie, Tennant, Daniel A., Wittmann, Christoph, Vander Heiden, Matthew G., Vazquez, Alexei, Vousden, Karen, Young, Jamey D., Zamboni, Nicola, Fendt, Sarah-Maria
Udgivet i Curr Opin Biotechnol (2015)

Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis

af Anastasiou, Dimitrios, Yu, Yimin, Israelsen, William J., Jiang, Jian-kang, Boxer, Matthew B., Hong, Bum Soo, Tempel, Wolfram, Dimov, Svetoslav, Shen, Min, Jha, Abhishek, Yang, Hua, Mattaini, Katherine R., Metallo, Christian M., Fiske, Brian P., Courtney, Kevin D., Malstrom, Scott, Khan, Tahsin M., Kung, Charles, Skoumbourdis, Amanda P., Veith, Henrike, Southall, Noel, Walsh, Martin J., Brimacombe, Kyle R., Leister, William, Lunt, Sophia Y., Johnson, Zachary R., Yen, Katharine E., Kunii, Kaiko, Davidson, Shawn M., Christofk, Heather R., Austin, Christopher P., Inglese, James, Harris, Marian H., Asara, John M., Stephanopoulos, Gregory, Salituro, Francesco G., Jin, Shengfang, Dang, Lenny, Auld, Douglas S., Park, Hee-Won, Cantley, Lewis C., Thomas, Craig J., Vander Heiden, Matthew G.
Udgivet 2012