Comparison of TCDD-elicited genome-wide hepatic gene expression in Sprague–Dawley rats and C57BL/6 mice

por Nault, Rance, Kim, Suntae, Zacharewski, Timothy R.
Publicado 2012

RNA-Seq versus oligonucleotide array assessment of dose-dependent TCDD-elicited hepatic gene expression in mice

por Nault, Rance, Fader, Kelly A, Zacharewski, Tim
Publicado en BMC Genomics (2015)

Comparisons of differential gene expression elicited by TCDD, PCB126, βNF, or ICZ in mouse hepatoma Hepa1c1c7 cells and C57BL/6 mouse liver

por Nault, Rance, Forgacs, Agnes L., Dere, Edward, Zacharewski, Timothy R.
Publicado 2013

Loss of liver-specific and sexually dimorphic gene expression by aryl hydrocarbon receptor activation in C57BL/6 mice

por Nault, Rance, Fader, Kelly A., Harkema, Jack R., Zacharewski, Tim
Publicado en PLoS One (2017)

Single-Nuclei RNA Sequencing Assessment of the Hepatic Effects of 2,3,7,8-Tetrachlorodibenzo-p-dioxin

por Nault, Rance, Fader, Kelly A., Bhattacharya, Sudin, Zacharewski, Tim R.
Publicado en Cell Mol Gastroenterol Hepatol (2020)

Lipidomic Evaluation of Aryl Hydrocarbon Receptor-Mediated Hepatic Steatosis in Male and Female Mice Elicited by 2,3,7,8-Tetrachlorodibenzo-p-dioxin

por Nault, Rance, Fader, Kelly A., Lydic, Todd A., Zacharewski, Timothy R.
Publicado en Chem Res Toxicol (2017)

Development of a Computational High-Throughput Tool for the Quantitative Examination of Dose-Dependent Histological Features

por Nault, Rance, Colbry, Dirk, Brandenberger, Christina, Harkema, Jack R., Zacharewski, Timothy R.
Publicado en Toxicol Pathol (2014)

Comparative Analysis of TCDD-Induced AhR-Mediated Gene Expression in Human, Mouse and Rat Primary B Cells

por Kovalova, Natalia, Nault, Rance, Crawford, Robert, Zacharewski, Timothy R., Kaminski, Norbert E.
Publicado en Toxicol Appl Pharmacol (2016)

Comparison of Hepatic NRF2 and Aryl Hydrocarbon Receptor Binding in 2,3,7,8-Tetrachlorodibenzo-p-dioxin–Treated Mice Demonstrates NRF2-Independent PKM2 Induction

por Nault, Rance, Doskey, Claire M., Fader, Kelly A., Rockwell, Cheryl E., Zacharewski, Tim
Publicado en Mol Pharmacol (2018)

2,3,7,8-Tetrachlorodibenzo-p-dioxin dose-dependently increases bone mass and decreases marrow adiposity in juvenile mice

por Fader, Kelly A., Nault, Rance, Raehtz, Sandi, McCabe, Laura R., Zacharewski, Timothy R.
Publicado en Toxicol Appl Pharmacol (2018)

2,3,7,8-Tetrachlorodibenzo-p-dioxin abolishes circadian regulation of hepatic metabolic activity in mice

por Fader, Kelly A., Nault, Rance, Doskey, Claire M., Fling, Russell R., Zacharewski, Timothy R.
Publicado en Sci Rep (2019)

2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) dysregulates hepatic one carbon metabolism during the progression of steatosis to steatohepatitis with fibrosis in mice

por Fling, Russell R., Doskey, Claire M., Fader, Kelly A., Nault, Rance, Zacharewski, Tim R.
Publicado en Sci Rep (2020)

Convergence of Hepcidin Deficiency, Systemic Iron Overloading, Heme Accumulation, and REV-ERBα/β Activation in Aryl Hydrocarbon Receptor-Elicited Hepatotoxicity

por Fader, Kelly A., Nault, Rance, Kirby, Mathew P., Markous, Gena, Matthews, Jason, Zacharewski, Timothy R.
Publicado en Toxicol Appl Pharmacol (2017)

2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD)-elicited effects on bile acid homeostasis: Alterations in biosynthesis, enterohepatic circulation, and microbial metabolism

por Fader, Kelly A., Nault, Rance, Zhang, Chen, Kumagai, Kazuyoshi, Harkema, Jack R., Zacharewski, Timothy R.
Publicado en Sci Rep (2017)

From the Cover: Coagulation-Driven Hepatic Fibrosis Requires Protease Activated Receptor-1 (PAR-1) in a Mouse Model of TCDD-Elicited Steatohepatitis

por Nault, Rance, Fader, Kelly A., Kopec, Anna K., Harkema, Jack R., Zacharewski, Timothy R., Luyendyk, James P.
Publicado en Toxicol Sci (2016)

2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) Alters Hepatic Polyunsaturated Fatty Acid Metabolism and Eicosanoid Biosynthesis in Female Sprague-Dawley Rats

por Doskey, Claire M., Fader, Kelly A., Nault, Rance, Lydic, Todd, Matthews, Jason, Potter, Dave, Sharratt, Bonnie, Williams, Kurt, Zacharewski, Tim
Publicado en Toxicol Appl Pharmacol (2020)

Pyruvate Kinase Isoform Switching and Hepatic Metabolic Reprogramming by the Environmental Contaminant 2,3,7,8-Tetrachlorodibenzo-p-Dioxin

por Nault, Rance, Fader, Kelly A., Kirby, Mathew P., Ahmed, Shaimaa, Matthews, Jason, Jones, A. Daniel, Lunt, Sophia Y., Zacharewski, Timothy R.
Publicado en Toxicol Sci (2016)

Toxicogenomic Evaluation of Long-term Hepatic Effects of TCDD in Immature, Ovariectomized C57BL/6 Mice

por Kopec, Anna K., Boverhof, Darrell R., Nault, Rance, Harkema, Jack R., Tashiro, Colleen, Potter, Dave, Sharratt, Bonnie, Chittim, Brock, Zacharewski, Timothy R.
Publicado 2013

Dose-Dependent Metabolic Reprogramming and Differential Gene Expression in TCDD-Elicited Hepatic Fibrosis

por Nault, Rance, Fader, Kelly A., Ammendolia, Dustin A., Dornbos, Peter, Potter, Dave, Sharratt, Bonnie, Kumagai, Kazuyoshi, Harkema, Jack R., Lunt, Sophia Y., Matthews, Jason, Zacharewski, Tim
Publicado en Toxicol Sci (2016)

The food contaminant acetamide is not an in vivo clastogen, aneugen, or mutagen in rodent hematopoietic tissue

por Moore, Martha M., Gollapudi, Bhaskar, Nagane, Rajendra, Khan, Nadeem, Patel, Manish, Khanvilkar, Tushar, Roy, Avani M., Ramesh, E., Bals, Bryan, Teymouri, Farzaneh, Nault, Rance, Bringi, Venkataraman
Publicado en Regul Toxicol Pharmacol (2019)