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Toxicogenomic Evaluation of Long-term Hepatic Effects of TCDD in Immature, Ovariectomized C57BL/6 Mice

Acute exposure to hepatotoxic doses of 2,3,7,8-tetrachloro- dibenzo-p-dioxin (TCDD) in mice is characterized by differential gene expression that can be phenotypically anchored to elevated levels of serum alanine aminotransferase, increased relative liver weights, hepatic steatosis, inflammation, an...

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Bibliografiset tiedot
Päätekijät: Kopec, Anna K., Boverhof, Darrell R., Nault, Rance, Harkema, Jack R., Tashiro, Colleen, Potter, Dave, Sharratt, Bonnie, Chittim, Brock, Zacharewski, Timothy R.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2013
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3807621/
https://ncbi.nlm.nih.gov/pubmed/23864506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kft156
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