Automated Dose-Response Analysis and Comparative Toxicogenomic Evaluation of the Hepatic Effects Elicited by TCDD, TCDF, and PCB126 in C57BL/6 Mice

The toxic equivalency factor (TEF) approach recommended by the World Health Organization is used to quantify dioxin-like exposure concentrations for mixtures of polychlorinated dibenzo-dioxins, -furans, and polychlorinated biphenyls (PCBs), including 2,3,7,8-tetrachlorodibenzofuran (TCDF) and 3,3′,4...

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Detalhes bibliográficos
Main Authors: Kopec, Anna K., Burgoon, Lyle D., Ibrahim-Aibo, Daher, Burg, Ashley R., Lee, Andrea W., Tashiro, Colleen, Potter, Dave, Sharratt, Bonnie, Harkema, Jack R., Rowlands, J. Craig, Budinsky, Robert A., Zacharewski, Timothy R.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Systems Toxicology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2955213/
https://ncbi.nlm.nih.gov/pubmed/20702594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfq236
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