Dose-Dependent Metabolic Reprogramming and Differential Gene Expression in TCDD-Elicited Hepatic Fibrosis

We have previously shown that in response to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-elicited NAFLD progression, central carbon, glutaminolysis, and serine/folate metabolism are reprogrammed to support NADPH production and ROS defenses. To further investigate underlying dose-dependent responses a...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Toxicol Sci
Prif Awduron: Nault, Rance, Fader, Kelly A., Ammendolia, Dustin A., Dornbos, Peter, Potter, Dave, Sharratt, Bonnie, Kumagai, Kazuyoshi, Harkema, Jack R., Lunt, Sophia Y., Matthews, Jason, Zacharewski, Tim
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2016
Pynciau:
Metabolic Reprogramming in TCDD Hepatic Fibrosis
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5139066/
https://ncbi.nlm.nih.gov/pubmed/27562557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfw163
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg