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From the Cover: Coagulation-Driven Hepatic Fibrosis Requires Protease Activated Receptor-1 (PAR-1) in a Mouse Model of TCDD-Elicited Steatohepatitis

Emerging evidence supports a role for environmental chemical exposure in the pathology of non-alcoholic fatty liver disease (NAFLD), a disease process tightly linked to increased activity of the blood coagulation cascade. Exposure of C57BL/6 mice to the persistent environmental contaminant 2,3,7,8-t...

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Detalhes bibliográficos
Publicado no:Toxicol Sci
Main Authors: Nault, Rance, Fader, Kelly A., Kopec, Anna K., Harkema, Jack R., Zacharewski, Timothy R., Luyendyk, James P.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5139072/
https://ncbi.nlm.nih.gov/pubmed/27613713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfw175
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