2,3,7,8-Tetrachlorodibenzo-p-Dioxin Alters Lipid Metabolism and Depletes Immune Cell Populations in the Jejunum of C57BL/6 Mice

2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) is a potent aryl hydrocarbon receptor agonist that elicits dose-dependent hepatic fat accumulation and inflammation that can progress to steatohepatitis. To investigate intestine—liver interactions that contribute to TCDD-elicited steatohepatitis, we examin...

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Detalhes bibliográficos
Publicado no:Toxicol Sci
Main Authors: Fader, Kelly A., Nault, Rance, Ammendolia, Dustin A., Harkema, Jack R., Williams, Kurt J., Crawford, Robert B., Kaminski, Norbert E., Potter, Dave, Sharratt, Bonnie, Zacharewski, Timothy R.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
TCDD and GUT Immune Cell Depletion
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5009443/
https://ncbi.nlm.nih.gov/pubmed/26377647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfv206
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